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New study on Hydroxychloroquine shows significant reduction in COVID-19 mortality

Without pointing the finger at any certain poster on this thread lol...

If you truly evaluate studies for a living, and mysteriously only criticize the studies which would benefit Trump politically, you have absolutely no business evaluating studies
 
Jack Hays said:
Trump has nothing to do with the thread topic.
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sorry jack, you're just being silly. If it wasnt about trump it would have occurred to JM to say it wasnt about trump. His first thought was to deflect to President Obama. Quite desperately I might add. And fyi, you should have posted to JM that President Obama has nothing to do with this thread. But you didn't. Again, trump touted an unproven treatment and you and yours are still desperately trying to justify trump's continued ignorance. And "injecting bleach" is also an unproven treatment. We can discuss that if you feel up to it.

jmotivator said:
No, the thread hasn't blown up in my face, Vern. The study stands and none of you can actually argue against the study findings, you just keep squawking about everything but the study.

It really makes you all look foolish.
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Jm, I'm not arguing the results of the study. I clearly stated that even if it turns out to be the magic bullet, trump had no business touting an unproven treatment. And you seem to be forgetting that he also touted injecting bleach. Notice a trend yet?
 
Vern said:
sorry jack, you're just being silly. If it wasnt about trump it would have occurred to JM to say it wasnt about trump. His first thought was to deflect to President Obama. Quite desperately I might add. And fyi, you should have posted to JM that President Obama has nothing to do with this thread. But you didn't. Again, trump touted an unproven treatment and you and yours are still desperately trying to justify trump's continued ignorance. And "injecting bleach" is also an unproven treatment. We can discuss that if you feel up to it.



Jm, I'm not arguing the results of the study. I clearly stated that even if it turns out to be the magic bullet, trump had no business touting an unproven treatment. And you seem to be forgetting that he also touted injecting bleach. Notice a trend yet?
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Nope. Sorry. Your partisan hackery is a poor response to a thread about research. Btw, I'll be voting for Biden.
 
jmotivator said:
Well, no. You gave a partisan argument that you clearly don't apply to studies you agree with. All you proved was that you are a fraud.

Granted, most of us need no further evidence on that matter.
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You either didn’t read it or can’t understand it.

Either way- that your problem.
 
Jack Hays said:
The thread recent "hockey stick" thread is there. 3G is likely still smudged up from being used to mop the floor.
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So it was an MWP redux thread.
How is that "Not even close"?
Maybe I wrong to expect the reply to make sense.
Whatever ... it was nice to see 3G's wingman pop in to lend support, if you can call it that.
 
Some might say this is the wrong point from the wrong guy, but there's nothing like tossing a Baby Ruth into the swimming pool.

[FONT=&quot][/FONT]
[h=1]Hypothesis: Restrictions on Hydroxychloroquine Contribute to the COVID-19 Cases Surge[/h][FONT=&quot]Although Hydroxychloroquine remains an approved drug and doctors can still prescribe it off-label, the FDA’s and NIH’s opinions have significant influence. State governments and medical boards adhere to the FDA opinion, in their subsequent recommendations. Even when HCQ is not banned outright, such opinion creates a chilling effect on pharmacies, doctors, hospitals, and, especially insurance companies.
Continue reading →
[/FONT]
 
[h=2]Hydroxycholoroquine *may* save half the people who were going to die of Covid[/h]
[h=3]Good news on the HCQ front[/h]The Henry Ford HCQ study is by no means decisive, but with death rates seemingly halved (sorta, maybe, kinda) — it does show how crazy it is to ban hydroxychloroquine. It also shows it’s low risk, and with all the conflicting studies out there, that there are a lot of ways to stuff things up.

With 10 million cases around the world it seems a bit incongruous that it’s taken so many months to get a trial this basic done with 2,000 patients. When the world only had 10,000 patients in January we already knew that the three drugs that were “fairly effective” were Remdesivir, Chloroquine and Ritonavir. As far back as February 13, the South Koreans were already recommending hydroxychloroquine and telling us the anti-virals should be “started as soon as possible.” They warned that after ten days, doctors “do not have to start antivirals”. South Korea was the experiment that worked — but we ignored it.
Speaking of slow research, the UK hydroxychloroquine trial that was stopped has restarted again as of three days ago. This is a trial to see if HCQ can prevent coronavirus in 40,000 healthcare workers.
[h=4]Perhaps half were saved?[/h]Of those enrolled in the trial, 87% of the people who got hydroxychloroquine (HCQ) survived. This was a lot better than the survival rate of those with neither HCQ nor Azithromycin which was 74%. Possibly half of those who died in the latter group might have been saved had they got HCQ. But, the study was not randomized, so we really don’t know.
Consider that those who got both HCQ and Azithromycin had a lower survival rate (80%) than for HCQ alone. This could be because of some extra risk with azithromycin, some bad interaction with both drugs in combination, or most likely, it was because the doctors gave both drugs to the sickest patients. Indeed, a lot more of the dual treatment patients spent time in the ICU (37%) compared to those in the “neither med” group (15%) and those treated with HCQ alone (20%). This is the problem with a non-randomized study. We don’t know if the doctors choice of who-to-treat skewed the results. It’s possible the combination of both could have been the best of all.
In comparison, in a randomized trial of the $3,000 remdesivir drug, there was a mortality rate of 8.0% (treated) versus 11.6% (untreated). Grein et al., 2020. So the HCQ was used on sicker patients with a higher mortality rate, but loosely seemed to have more effect. Given the bargain price of HCQ, long history, mass supplies, and known potential against SARS-1, we wonder why it hasn’t had a proper randomized trial too.
Finally some good coronavirus news for the Trump team. This result will help encourage people to sign up to trials and give doctors back some confidence to use it.
No heart related side effects
One thing it does show is that there were no heart-related side effects, which means it can be low risk and low cost, if done properly. Doctors already know how to screen people who are at risk, which is hardly a surprise given that doctors write 5 million prescriptions for this each year in the US and have done for decades. So let’s get cracking and use it.
Indeed, this shifts the ethical battle — is it fair not to treat patients?
Steroids muddy the result
Keep reading →
 
Jack Hays said:
Sorry. I was doing too many things at once. It's here. Enjoy.




►Hockey stick confirmed yet again.
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I read it for almost 100 posts and oh dear god that was ugly.
I'm sorry, but I can only watch authority bias as a substitute for understanding in very small doses but that's all you got on that thread.
It gets worse when, as on this thread, someone has convinced himself that THEY are the authority.
 
bubbabgone said:
I read it for almost 100 posts and oh dear god that was ugly.
I'm sorry, but I can only watch authority bias as a substitute for understanding in very small doses but that's all you got on that thread.
It gets worse when, as on this thread, someone has convinced himself that THEY are the authority.
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It doesn't go much further than that. I suggest you finish it. You'll feel better.
 
Jack Hays said:
Some might say this is the wrong point from the wrong guy, but there's nothing like tossing a Baby Ruth into the swimming pool.

[FONT="][URL="https://wattsupwiththat.com/2020/07/05/hypothesis-restrictions-on-hydroxychloroquine-contribute-to-the-covid-19-cases-surge/"]
image-8.png
[/URL][/FONT]
[h=1]Hypothesis: Restrictions on Hydroxychloroquine Contribute to the COVID-19 Cases Surge[/h][FONT="][FONT=inherit]Although Hydroxychloroquine remains an approved drug and doctors can still prescribe it off-label, the FDA’s and NIH’s opinions have significant influence. State governments and medical boards adhere to the FDA opinion, in their subsequent recommendations. Even when HCQ is not banned outright, such opinion creates a chilling effect on pharmacies, doctors, hospitals, and, especially insurance companies.[/FONT]
[FONT=inherit][URL="https://wattsupwiththat.com/2020/07/05/hypothesis-restrictions-on-hydroxychloroquine-contribute-to-the-covid-19-cases-surge/"]Continue reading →[/URL][/FONT]
[/FONT]
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We'd see the same charts across Europe too if this were the case.
 
Jack Hays said:
It doesn't go much further than that. I suggest you finish it. You'll feel better.
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You're killing me.
So I continued and saw "I dont read ****ty blogs".
Why did you make me read that kind of crap?
It was clear he knew the jig was up and he moonwalked clear off that thread ... and apparently onto this one.
Satisfying result, yes, but instead of admitting mistakes he posts links he doesn't read.
The capper was quoting Mann's book today as a defense for the hockey stick's ****ty proxy choices.
 
bubbabgone said:
You're killing me.
So I continued and saw "I dont read ****ty blogs".
Why did you make me read that kind of crap?
It was clear he knew the jig was up and he moonwalked clear off that thread ... and apparently onto this one.
Satisfying result, yes, but instead of admitting mistakes he posts links he doesn't read.
The capper was quoting Mann's book today as a defense for the hockey stick's ****ty proxy choices.
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As I said, it’s over your head.
 
Slavister said:
We'd see the same charts across Europe too if this were the case.
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The E. U. ban on HCQ wasn't put into place until May 26, and it's still being used in Spain, Germany, Turkey, and other Eastern European countries
 
ReubenSherr said:
The E. U. ban on HCQ wasn't put into place until May 26, and it's still being used in Spain, Germany, Turkey, and other Eastern European countries
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As you continue to flog this, ANOTHER study was stopped for futility on July 4th from the WHO. IN this study, they've reported on July 1st that 5500 patients have been already enrolled.

WHO discontinues hydroxychloroquine and lopinavir/ritonavir treatment arms for COVID-19

WHO today accepted the recommendation from the Solidarity Trial’s International Steering Committee to discontinue the trial’s hydroxychloroquine and lopinavir/ritonavir arms. The Solidarity Trial was established by WHO to find an effective COVID-19 treatment for hospitalized patients.

The International Steering Committee formulated the recommendation in light of the evidence for hydroxychloroquine vs standard-of-care and for lopinavir/ritonavir vs standard-of-care from the Solidarity trial interim results, and from a review of the evidence from all trials presented at the 1-2 July WHO Summit on COVID-19 research and innovation.

These interim trial results show that hydroxychloroquine and lopinavir/ritonavir produce little or no reduction in the mortality of hospitalized COVID-19 patients when compared to standard of care. Solidarity trial investigators will interrupt the trials with immediate effect.

For each of the drugs, the interim results do not provide solid evidence of increased mortality. There were, however, some associated safety signals in the clinical laboratory findings of the add-on Discovery trial, a participant in the Solidarity trial. These will also be reported in the peer-reviewed publication.
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ReubenSherr said:
The E. U. ban on HCQ wasn't put into place until May 26, and it's still being used in Spain, Germany, Turkey, and other Eastern European countries
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So? Countries that DID stop using are NOT having the same graph... So, it does not matter if some countries are still using it - that does not invalidate my observation.
 
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ReubenSherr said:
Did these countries show a sharp downturn in their curve after May 26?
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The claim was that our spike in cases is because of stopping HCQ. Other countries did not have such spike. No "sharp" downturn is needed here for my point to remain valid.
 
Slavister said:
The claim was that our spike in cases is because of stopping HCQ. Other countries did not have such spike.
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Sorry, I misinterpreted- that claim is reaching too far

I do think, though, that our numbers would be a lot better if hospitals hadn’t been dissuaded from giving HCQ to patients in early stages of the illness. One thing is clear at this point, HCQ is not dangerous
 
jmotivator said:
https://www.ijidonline.com/article/S1201-9712(20)30534-8/fulltext

Treatment with Hydroxychloroquine, Azithromycin, and Combination in Patients Hospitalized with COVID-19




A multi-hospital study found that elderly patients treated with hydroxychloroquine had a 66-71% mortality rate ratio reduction compared to patients who weren't administered the drug, with no observed side effects.
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Well, well, I haven't seen this study plastered all over the liberal MSM. They would rather have people die than admit Trump was right all along.
 
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