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Hydroxychloroquine. It’s over.

apdst said:
Idiotic statements like the one you posted are beyond comprehension.
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There's a good reason you are so often ridiculed. Your comprehension skills rival those of a 12 year old.
 
Greenbeard said:
Huh, so the answer to "What have you got to lose?" is "your life."

I wonder how many folks Trump and his fellow hucksters in the rightwing infotainment industry killed by hawking an unproven treatment.
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Increased mortality doesn't mean anything.
 
apdst said:
No, we're here to ridicule your celebration of failure.
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What failure? We now have even more evidence of what doesn't work. That's not a failure. It's additional knowledge. That is a victory. At some point even you Trumpsters will come around and realize it's time to move on to the next unproven treatment.
 
Why accept an observational study when clinical studies are underway? I'll wait for a real study, not this garbage.
 
There are also observational studies pointing to HCQ benefits, with just as much data as this one- I’m on my phone and can’t Copy and paste but will link site tonight to one study in particular

The problem is the liberal media refers to the same few “anti-HCQ” studies over and over so many times that the studies coming out supporting it get buried in search engines

Also, notice the publisher of the OP’s article is careful to say that he/she does not necessarily support the writer’s opinions, even if reference to his analysis of this study

The title of this thread is pretty misleading - It’s based on an editorial, the opinion of one journalist which his publisher does not necessarily back
 
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Re: Hydroxychloroquine. It’s over.

Visbek said:
No, there hasn't.
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Actually, there has been... If you were really interested from a human standpoint, rather than a political one, you would have known that.

Drug Combo with Hydroxychloroquine Promising: NYU Study
May. 12, 2020

Researchers at NYU's Grossman School of Medicine found patients given the antimalarial drug hydroxychloroquine along with zinc sulphate and the antibiotic azithromycin were 44 percent less likely to die from the coronavirus.

Drug Combo with Hydroxychloroquine Promising: NYU Study
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Early Hydroxychloroquine Is Associated with an Increase of Survival in COVID-19 Patients: An Observational Study
May 5, 2020

Results: 48.8 % of patients not treated with hydroxychloroquine died. 22% of those treated with hydroxychloroquine died. Hydroxychloroquine increased the mean cumulative survival in all groups from 1.4 to 1.8 times. This difference was statistically significant in the mild group.

Conclusions: in a cohort of 166 patients from 18 to 85 years hospitalised with COVID-19, hydroxychloroquine treatment with 800mg added loading dose increased survival when patients were admitted in early stages of the disease.

Early Hydroxychloroquine Is Associated with an Increase of Survival in COVID-19 Patients: An Observational Study[v1] | Preprints
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Early treatment of COVID-19 patients with hydroxychloroquine and azithromycin: A retrospective analysis of 1061 cases in Marseille, France
May 3, 2020

Results: A total of 1061 patients were included in this analysis (46.4% male, mean age 43.6 years – range 14–95 years). Good clinical outcome and virological cure were obtained in 973 patients within 10 days (91.7%).

Conclusion: Administration of the HCQ+AZ combination before COVID-19 complications occur is safe and associated with a very low fatality rate in patients.

Early treatment of COVID-19 patients with hydroxychloroquine and azithromycin: A retrospective analysis of 1061 cases in Marseille, France - ScienceDirect
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Hydroxychloroquine application is associated with a decreased mortality in critically ill patients with COVID-19.
May 1, 2020

568 critically ill COVID-19 patients with a median age of 68 (57, 76) years old. 48 were given a treatment of Hydroxychloroquine. Mortalities are 18.8% (9/48) in HCQ group and 45.8% (238/520) in NHCQ group.

Hydroxychloroquine vs. COVID-19 – The Economic Standard
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Grim17 said:
Three letters say it all....

T D S

.
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Stop trying to gaslight people.

There is nothing deranged about not wanting a stupid, incompetent, and corrupt individual like Trump to be President.

On the other hand, there is something very deranged about wanting a stupid, incompetent, and corrupt individual like Trump to be President.

Trump supporters should stop putting their own selfish political interests ahead of the country's interests. It should be abundantly clear by now that Trump is totally unfit to be President.
 
ReubenSherr said:
There are also observational studies pointing to HCQ benefits, with just as much data as this one- I’m on my phone and can’t Copy and paste but will link site tonight to one study in particular

The problem is the liberal media refers to the same few “anti-HCQ” studies over and over so many times that the studies coming out supporting it get buried in search engines

Also, notice the publisher of the OP’s article is careful to say that he/she does not necessarily support the writer’s opinions, even if reference to his analysis of this study

The title of this thread is pretty misleading - It’s based on an editorial, the opinion of one journalist which his publisher does not necessarily back
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What?

This study has six times the number of patients reported in trials with these drugs COMBINED.

It’s not based on an editorial, it’s based on a boatload of data showing no benefit and considerable harm.

And the ‘liberal media’ and search engines are not how medical decision making is determined. Physicians, pharmacists and public health officials are aware of all the data, and make decisions based upon that.

This study is also peer reviewed in a very good journal. That increases the strength of evidence, in comparison to this pre-print stuff which is hopefully going to stop soon.
 
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ReubenSherr said:
Here's an abstract for an observational study exclusively based on Early HCQ Treatments, similar to what Trump and his physician are advocating...

Early Hydroxychloroquine Is Associated with an Increase of Survival in COVID-19 Patients: An Observational Study[v2] | Preprints

It's observational, but carries just as much weight as the observational study which was the entire basis for this thread
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166 patients at one site vs 15,000 worldwide.

As I told you before, you really, really don’t know what you’re talking about.
 
Grim17 said:
The micro-second Donald Trump suggested that hydroxychloroquine might be a drug that could help in the fight against the coronavirus, the left made discrediting the drug their top priority... In the eyes of those infected by TDS, hydroxychloroquine must fail or Trump wins. That's why they are celebrating this study.

.
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No.
I don't want ANY president promoting ANY drug whatsoever unless they graduated medical school.
I don't care if it's HCQ, Remdesivir or aspirin.
If there is a drug being explored, presidents need to let the medical professionals make decisions free of political pressure of any kind.

I also don't want the guy who fixed my automatic transmission telling me what codec to use when I upload a video to the internet.
I also don't want my local police chief telling what camera I should be okay to use.
I also don't want my doctor pressuring me on lens choices.
I also don't want the physics instructor at the local community college weighing in on whether they think it's safe for me to take Viagra.
 
Slavister said:
Trump and the Cult will probably come out any minute now either

(a) to dispute the fake news Deep State neverTrumper study

or

(b) claim that they said all along that HCQ was terrible, way before anyone else was saying it.

Which will it be? Which will it be? The suspense is killing me... :yawn:
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It will probably be "positively towards the negative."
 
ludin said:
Not sure what they are celebrating. The drug was never being used to combat covid 19 itself.
it was being used to help in the relief of lung distress that the virus was causing.

We all know that such treatments only work so well. If someone already had the virus and existing lung issues
then there is a great chance that the drug would not do anything or have little effect.

in a healthy normal person i could help enough to aviliate some of the lung distress.
no one in their right mind suggested that this was a cure all for covid19 only that it helped
in some cases with lung functions.
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Does Trump have lung distress?
 
Grim17 said:
Unless medical science comes up with a way to do a brain transplant, Joe Biden for president is going to be a tough sell... Especially after the first presidential debate and the American people see how diminished his mental capacity has become.

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LOL, you have some advance insight into his mental capacity?
 
JMR said:
LOL, you have some advance insight into his mental capacity?
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You can't make declarations about a person's mental faculties unless you're a doctor who has directly examined the patient! Or if you're a conservative.
 
Linc said:
Let’s see how STD-caused brain-dementia patient Trump garbles a response to damning evidence of the dangerous failures of HCQ. Wow. Science illiteracy at its Max.
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If a female moderator asks such a question, he can fall back on his favorite method of labelling her nasty. His devotees eat that up.
 
Re: Hydroxychloroquine. It’s over.

Grim17 said:
Actually, there has been... If you were really interested from a human standpoint, rather than a political one, you would have known that.
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Or, not.

The Marseilles study was the first one which, as I mentioned, was retracted.

The Spanish study you linked was an observation of 220 patients. The Lancet study looked at 90,000 patients. Which do you think is more likely to produce useful information?

The NYU study wasn't hydroxychloroquine vs nothing. It was "hydroxychloroquine with zinc sulfate" vs "hydroxychloroquine with zinc sulfate and azithromycin." The author believes that zinc sulfate may be doing most of the work, and hydroxychloroquine might make the zinc sulfate more effective.

Your last link isn't a study. It's a collection of links, which includes the other three you linked. That page includes the China study I mentioned; the retracted Marseilles study; another French study that was withdrawn; announcements of studies, including some that haven't even started yet, and won't end until next year; completed studies that show how hydroxychloroquine isn't effective (e.g. the NEJM study); several articles that theorize how hydroxychloroquine might work (i.e. not studies that prove it does work); a study on famotidine (i.e. Pepcid).

Oh, and the Lancet study observed 90,000 patients. The second and third largest studies I'm aware of is 1400 patients, which is the NEJM and the VA study -- both of which found no benefit to hydroxychloroquine.

So basically, that raises the total of valid pro-hydroxychloroquine studies has gone from one to... two. That's enough to justify further study, but it certainly isn't an avalanche of evidence in favor of hydroxychloroquine.
 
ecofarm said:
Trump, and Trumpers, want old people, minorities and the poor to die. They believe that will boost the economy and improve the gene pool (both minorities and the poor). They spend all day claiming and crying about non-Trumpers wanting an apocalypse to get Trump out of office. Like Trump, at this point, needs any help being shown the door.

It's a death cult. If Trump had his way, they'd all be taking HCQ.
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I've not met a Trumper who seems likely to improve the gene pool. I guess it comes down to what the definition of improve is.
 
In other news, remdisivir looked pretty good in this trial published in NEJM today.

It’s no ‘game changer’, but a nice base to use to combine with other therapies.

Hopefully, we will be able to get some drugs and techniques to manage this disease much better as it comes back in a second wave or third wave in the fall. With therapies, we can reduce (not eliminate!) risk of death and ICU stays.


https://www.nejm.org/doi/full/10.1056/NEJMoa2007764?query=featured_home
 
Grim17 said:
I'm not talking about rallying around the president, I'm talking about people putting political differences aside, putting their partisan bickering on hold and coming together as a country to meet adversity head on.

The left hasn't skipped a beat since this crisis began. Instead of dropping the partisan BS and focusing on virus and the effect it's having on every American family, they've used this crisis to ramp up their attacks on Trump and republicans. Their loyalties are, and have remained, politics first, and everything else a distant second. It's just disgusting.

.
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Are you equally disgusted with Trump's attacks on democratic governors? What's your disgust level with his idiot sons claiming that the virus is a hoax created by the left?

Or is your disgust just a partisan issue?
 
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