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A vaccine on the near horizon?

RAMOSS said:
One group said that IF testing goes well, they expect to give the vaccine for 'compassionate care' by Sept 30th. (mind you, the cravat is the testing for it).
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Unless a powerful politician says "NOW!"
 
OldFatGuy said:
My son tells me he and his colleagues have encountered infected patients with few or no symptoms, some of them being high risk from other problems. He has also said the worst sufferers, for the most part, seem to be blood type A, which may or may not be a factor. He also mentioned inability to metabolize specific vitamins, but no certainty of before or after. We didn't have time to get into details, he wanted to know how his kids were doing, and of course I told him they are a PITA. Got a chuckle. He's the father of the twins and hasn't seen them for two weeks. He and his wife, an RN, are staying at first class hotel, which belongs to one of my longtime friends. On the cuff, along with about 20 other doctors and 30 or so nurses. Unfortunately, they can't enjoy it, just coming back to their rooms with take out, showering, changing and passing out from exhaustion before going back to work. His wife makes a point of speaking with the kids once a day, he doesn't have that luxury. There older kids have been in and out for meals, checking on siblings and cousins, volunteering with meals on wheels, delivering meds, and similar activities. Good kids.
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Your son says, yet 4 months into this thing official channels have nothing much to say on this point, which means that if he is correct then I am proven largley correct that the elite have failed......that Trump and all in his Army are completely correct the main point of their objection to the Ruling Class...

Put that in your pipe and smoke it...
 
iguanaman said:
Not from a vaccine that's for sure but there is still hope that an effective treatment might still come in time to save some lives.
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Oh yes

Scientist and doctors the world over working non stop to find effective treatments and vaccine. I have faith in science that this can be beat.
 
Hawkeye10 said:
Your son says, yet 4 months into this thing official channels have nothing much to say on this point, which means that if he is correct then I am proven largley correct that the elite have failed......that Trump and all in his Army are completely correct the main point of their objection to the Ruling Class...

Put that in your pipe and smoke it...
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There is a paper written by Chinese researchers about the blood group anomaly. Sorry to burst your bubble. "Trump and his army" are still morons.

Some Blood Types May Be Slightly More Susceptible to COVID-19, Paper Suggests
 
OldFatGuy said:
Not a time for older established restrictions. I'd have thought the progressives would celebrate the cutting of red tape.
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Progressives are typically the ones that put the red tape up.
 
Nap said:
Progressives are typically the ones that put the red tape up.
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"Do as you are told, or else you are going overboard....Do U understand Serf?".
 
Nap said:
Progressives are typically the ones that put the red tape up.
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What a silly comment, Nap. I expect better of you. Government, by both sides, loves red tape.

Lets hope the Pres and the party leaders get around this obstacle mucho quicko.
 
Casper said:
Don't count on seeing one in 2 months, even fast tracking it still includes a lot of testing and an approval process. Once approved it must be produced and distributed, they need 377,000,000 doses to cover the population. All takes time and those with health conditions and those over 60 will get the vaccine first. MAYBE by the end of the year.
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Hopefully by the end of next year.
 
OldFatGuy said:
It hasn't been around for that long. No need for a vaccine. Basically it is a variant of the cold virus. We have not been able to cure the common cold because if constantly mutates by almost imperceptible variations, thus multiples of strains. Similar behavior to flu viruses. We develop flu vaccines that only address a percentage of the mutated variations, strains. Covoid 19 has been identified as 4 different strains, 3 predatory for humans, and not very dissimilar from SARS and HIV in basic structure. Most vaccines work by getting the immune system to create and replicate antibodies which prey on the targeted virus. Not very easy when there is little understanding of how the virus replicates. Duplicating a virus in a lab, does not necessarily mean that there is an understanding of the viral replication mechanisms. Therefore providing instructions for antibody structures is difficult at the least. Almost incidental when it occurs.

It took a decade to identify the various polio strains before truly effective use was acceptable. First resolved in 1946 and used on a human researcher injecting himself but not released for general use until 1955, and then withdrawn temporarily for an assortment of reasons. Despite how much we've learned about viruses, there is much more we do not know. None which means this particular vaccine cannot be fast tracked and distributed like no other previously. Necessity is the mother of invention.

Maybe it will work, maybe it won't, perhaps it will be worse than the disease? Nothing ventured, nothing gained. No pain, no gain. How many of the dying will volunteer for its use? Now let all the experts chime in.
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It is my understanding that if a person already has a disease it is too late to vaccinate him or her form the disease.

Vaccines prevents the person from getting the disease but once a person has that disease it is too late for a vaccine to work.
 
minnie616 said:
Hopefully by the end of next year.
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I will be happy if they can do it sooner, the end if the year sounds closer to the reality, 2 months is wishful thinking.
Be Safe
 
By autumn perhaps. Has to be tested thoroughly.
 
Hawkeye10 said:
Your son says, yet 4 months into this thing official channels have nothing much to say on this point, which means that if he is correct then I am proven largley correct that the elite have failed......that Trump and all in his Army are completely correct the main point of their objection to the Ruling Class...

Put that in your pipe and smoke it...
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Note his observation is just that, speculation based on the word "seem." "It is what we don't know that kills us." - anonymous
 
minnie616 said:
It is my understanding that if a person already has a disease it is too late to vaccinate him or her form the disease. Vaccines prevents the person from getting the disease but once a person has that disease it is too late for a vaccine to work.
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That depends on the nature of the vaccine. Sometimes the vaccine can also be used in treatment, sometimes not. For example, the proteins extracted from plasma can do both.

A lot of the clinical work done on SARS over the last decade is applicable, since the two are caused by closely related corona viruses. I don't have a source, but I think at least one of the serums in testing was initially developed for SARS.
 
minnie616 said:
It is my understanding that if a person already has a disease it is too late to vaccinate him or her form the disease.

Vaccines prevents the person from getting the disease but once a person has that disease it is too late for a vaccine to work.
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Vaccines vary, a general term. Administration of a vaccine, for an already infected patient, that interferes with a virus's replication ability allows the body's own mechanisms to fight a lesser foe. It can also instruct (for want of a better word) the infected patient's mechanisms how to attack the invading microbe. Generally, a vaccine introduces antibodies into a host, with hope the host will replicate the antibodies to prey on the invading microbe. No vaccine can reverse damage already accomplished, therefore a vaccine like that for polio, may stop progress of the disease, but not reverse damage to nerve and muscle tissue already established.
 
Hawkeye10 said:
Where is WHO?

Where is the CDC?

Where is the FDA?

Where are the so-called journalists?






OOPS
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Read the article. It is a strange anomaly not a cure. People of all blood types get very sick from Covid 19.
 
OldFatGuy said:
There is nothing to stop a general release of the data for creating the vaccine so every nation can use or build their own labs to produce it, except greed.
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Everyone involved is already working together on vaccines, antivirals, and understanding the virus.

That doesn't change anything. The reality is that testing a vaccine takes a long time. Short cuts all but guarantee that the vaccine either won't be effective enough, or that side effects are both unknown and harmful. Not only is that harmful in its own right, any problems with the vaccine will result in damaging critically needed trust, and a high percentage of people refusing to take it.

In other words, Star Trek is not reality. You can't cook up a cure in 2 minutes of screen time.


Ask a patient with stage 4 cancer about hope vs safe. How many companies are now producing ventilators? Of course we can take shortcuts.
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No, we can't.

We can work fast, but not if it compromises quality and/or results. For example, medical supplies rushed out of China are turning out to be poor quality, which puts health care providers at great risk. Needless to say, that's a disaster for everyone involved, so the Chinese government is clamping down on manufacturers to ensure quality.

Also, the whole point of social distancing is to buy us as much time as possible.


I am a human guinea pig for medical research. Without volunteering to do so, I'd be bedridden at the least, or dead.... The FDA said no, my lawyers said yes.
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Yet another non-credible, completely unprovable, and convenient claim by OFG :roll:

That's not how it works. If a drug is already approved, your doctor can usually prescribe it off-label. Your lawyers won't be involved in that.

The FDA does sometimes allow emergency or compassionate usage. There are strict conditions for emergency usage -- e.g. a life-threatening condition that requires immediate use; no alternatives; no time to wait. In that case, lawyers may be involved, but the FDA has to say yes.
 
OldFatGuy said:
It hasn't been around for that long. No need for a vaccine. Basically it is a variant of the cold virus.
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Stop spreading misinformation.

A vaccine is absolutely critical. And COVID-19 is a variant of coronaviruses like SARS and MERS, not a common cold like a rhinovirus.


We have not been able to cure the common cold because if constantly mutates by almost imperceptible variations, thus multiples of strains.
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And we have been able to eradicate entire diseases like smallpox, as well as severely restrict diseases like mumps, measles, rubella, chicken pox and more.

We don't know if COVID-19 will mutate. Even if it does, developing a seasonal vaccine will be enormously beneficial.
 
Visbek said:
Everyone involved is already working together on vaccines, antivirals, and understanding the virus.
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Everyone is not working together. There are independent researchers acting without connection to others, and different government efforts in other countries not cooperating with anyone else.

So many assumptions, so much crap.

Do not presume to claim you know what my lawyers accomplished in my behalf. You have no knowledge of the circumstances nor, obviously, a clue as to how quality attorneys can provide pressures you haven't dreamt of. The FDA is a bunch of old men more concerned with protecting their own establishment and powers than the needs of people. They are far from the last word. Just one more bureaucratic agency.

If we have learned nothing, we have learned there are no guarantees in this life.
 
Visbek said:
Stop spreading misinformation.

A vaccine is absolutely critical. And COVID-19 is a variant of coronaviruses like SARS and MERS, not a common cold like a rhinovirus.



And we have been able to eradicate entire diseases like smallpox, as well as severely restrict diseases like mumps, measles, rubella, chicken pox and more.

We don't know if COVID-19 will mutate. Even if it does, developing a seasonal vaccine will be enormously beneficial.
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Corona viruses are variants of rhinoviruses. The same family of viruses. No different than comparing proboscis monkeys to you.

And of course, those outbreaks of small pox, according to you, are not real.

Who is saying vaccines are of no value? What is this BS from you?

Is there any microbe that will not mutate? Is there any living being that will not mutate? Your profundity is not profound.
 
OldFatGuy said:
Everyone is not working together.
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No, dude. This is not business as usual. Researchers are working together, sharing data, dropping almost everything else.
Covid-19 Changed How the World Does Science, Together - The New York Times


Do not presume to claim you know what my lawyers accomplished in my behalf.
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I know that you can't just have your lawyer send the FDA a nastygram and get whatever unapproved medication you want. That's all I need to know.
 
OldFatGuy said:
There is nothing to stop a general release of the data for creating the vaccine so every nation can use or build their own labs to produce it, except greed. Ask a patient with stage 4 cancer about hope vs safe. How many companies are now producing ventilators? Of course we can take shortcuts.

I am a human guinea pig for medical research. Without volunteering to do so, I'd be bedridden at the least, or dead. All protocols are being ignored. Instead I'm pleasing myself by making music every day and cooking for 14 or more, as well as doing the food shopping, taking long walks with my dog and making love to my wife. The FDA said no, my lawyers said yes. So it goes.
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I'll volunteer too! I would enjoy making music everyday and making love to your wife too! Where do I sign up?
 
Visbek said:
Stop spreading misinformation.

A vaccine is absolutely critical. And COVID-19 is a variant of coronaviruses like SARS and MERS, not a common cold like a rhinovirus.
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it will last forever...


"RUSH LIMBAUGH (HOST): But I’m telling you, folks, I have — there’s so many red flags about things happening out there. This coronavirus, they’re just — all of this panic is just not warranted. This, I’m telling you, when I tell you — when I’ve told you that this virus is the common cold. "
 
OldFatGuy said:
Corona viruses are variants of rhinoviruses.
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:roll:


And of course, those outbreaks of small pox, according to you, are not real.
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They aren't. The last case of smallpox was in 1977. Look it up.


Who is saying vaccines are of no value?
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You did. You wrote "It hasn't been around for that long. No need for a vaccine. Basically it is a variant of the cold virus."


Is there any microbe that will not mutate?
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Basically, yes -- or at least, not so quickly that vaccines are ineffective (as, again, you were suggesting in your post). Yet again! Vaccines against chicken pox, measles, mumps, rubella and more are highly effective, year after year.

Even when it does mutate, vaccines are still highly beneficial. E.g. they make the flu vaccine before knowing exactly which strain will become dominant, but it still reduces the impact of any flu strain.
 
Originally Posted by Hawkeye10 View Post
Where is WHO?

Where is the CDC?

Where is the FDA?

Where are the so-called journalists?
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WHO's on first......
 
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