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Hydroxychloroquine and Chloroquine for Thousands in New York

Jack Hays said:


Hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19: a multinational registry ...

The Lancet·1 day ago
Click to expand...
https://www.thelancet.com/lancet/article/s0140673620311806

We were unable to confirm a benefit of hydroxychloroquine or chloroquine, when used alone or with a macrolide, on in-hospital outcomes for COVID-19. Each of these drug regimens was associated with decreased in-hospital survival and an increased frequency of ventricular arrhythmias when used for treatment of COVID-19.
[SOURCE - your cited article]
​

Jack Hays said:


What a big Covid-19 study on malaria drugs tells us — and what it doesn't

Stat·1 day ago
Click to expand...

A new study underlines safety concerns about using the malaria drugs hydroxychloroquine and chloroquine to treat Covid-19, and heightens questions about whether or not the drugs are effective at all.

The study, which was published in the Lancet, cannot answer the question of whether or not hydroxychloroquine and chloroquine can help patients fight off Covid-19 or whether the drugs increase or decrease the death rates in those patients. Those answers can only come from large studies in which patients are randomly assigned to either receive the drugs or a placebo. Dozens of such studies are ongoing.

The results, however, are a reminder of the risks of deciding to use medicines without clear evidence of their benefits and risks.
[SOURCE - your cited article]
​

Jack Hays said:
No evidence of benefit for chloroquine and hydroxychloroquine in COVID-19 patients, study finds

ScienceDaily·1 day ago
Click to expand...

A new study finds that the use of chloroquine or hydroxychloroquine is linked to increased rates of mortality and heart arrhythmias among hospital patients with COVID-19. The authors suggest that these drug regimens should not be used to treat COVID-19 outside of clinical trials and urgent confirmation from randomised clinical trials is needed.
[SOURCE - your cited article]
​

See how easy it is to make a post that is actually informative?
 
QUICK SUMMARY OF Comparative COVID-19 (Total Deaths/Total Cases) Mortality Rates
- Data source - COVID-19 Coronavirus Pandemic -
​

20/04/15 – World (128,011/2,017,174) 6.35% / USA (26,064/* 614,246) 4.24% / Canada (* 903/27,063) 3.34%

20/04/20 – World (166,271/2,430,733) 6.84% / USA (40,743/* 767,189) 5.31% / Canada (1,587/35,056) 4.53%

20/04/25 – World (198,073/2,850,387) 6.95% / USA (52,217/* 925,758) 5.64% / Canada (2,302/43,888) 5.25%

20/04/30 – World (229,179/3,244,537) 7.07% / USA (61,680/1,064,832) 5.79% / Canada (2,996/51,597) 5.81%

20/05/05 – World (252,950/3,665,418) 6.90% / USA (69,925/1,213,010) 5.76% / Canada (3,854/60,772) 6.34%

20/05/10 – World (280,986/4,126,870) 6.81% / USA (80,044/1,347,411) 5.94% / Canada (4,693/67,707) 6.93%

20/05/15 – World (304,242/4,558,839) 6.67% / USA (86,970/1,459,684) 5.96% / Canada (4,472/73,401) 7.45%

20/05/16 – World (309,047/4,649,079) 6.65% / USA 988,523/1,484,579) 5.96% / Canada (5,562/74,613) 7.45%

20/05/17 – World (313,794/4,750,064) 6.61% / USA (91,134/1,509,341) 5.97% / Canada (5,679/75,864) 7.49%

20/05/18 – World (317,756/4,833,022) 6.57% / USA (90,993/1,528,931) 5.95% / Canada (5,782/77,022) 7.51%

20/05/19 – World (320,560/4,916,991) 6.52% / USA (91,985/1,550,539) 5.93% / Canada (8,842/78,072) 7.48%

20/05/20 – World (325,421/5,011,163) 6.49% / USA (93,558/1,571,131) 5.95% / Canada (5,912/79,112) 7.47%

20/05/21 – World (330,768/5,122,280) 6.46% / USA (95,016/1,595,081) 5.96% / Canada (6,031/80,142) 7.53%

20/05/22 – World (335,223/5,227,331) 6.41% / USA (96,337/1,621,772) 5.94%/ Canada (6,152/81,324) 7.56%

20/05/23 – World (340,616/5,338,084) 6.38% / USA (97,687/1,647,043) 5.93% / Canada (6,250/82,480) 7.58%

20/02/24 – World (344,513/5,435,984) 6.34% / USA (98,076/1,668,493) 5.92% / Canada (6.355/83,621) 7.60%
​

More Americans have now died from COVID-19 than died due to

-the Normandy Campaign (29,204),

influenza in an average year (~35,000),

the Korean War (36,516)-

the Vietnam War (58,209).​

The next "Grim Mortality Milestone” is the number of American deaths

-in the Normandy Campaign (29,204),

from influenza in an average year (~35,000),

in the Korean War (36,516),

in the Vietnam War (58,209)-

in World War I (116,516) or the 1957 “Asian Flu” (~116,000).

*********************************************​

[M]-D≤10,300 Prediction is incorrect and is 858.31% too LOW (and the error is RISING)
[F]-100,000 ≤ D ≤ 200,000 Prediction is incorrect and is 1.29% too HIGH (and the error is FALLING)

[M] - Dr. Mushmouth (BA [Pla-Doh], BS [Statistics], PhD [Finger Painting] - University of Numerology)
[F] - Dr. Fauci (BA - Holy Cross, MD - Columbia)

25+ days since MM103/2+
13+ days since MM103/2+
5.26 days until MM103/2+

Rolling 7 day US average deaths per day TODAY is 1,225 (YESTERDAY it was 1,309).
 
Brazil includes chloroquine in treatment of mild cases of COVID-19
Brazil includes chloroquine in treatment of mild cases of COVID-19 | Agencia Brasil

It is up to the doctor to prescribe the drug and the patient to agree

Published in 20/05/2020 - 15:33 By Andreia Verdélio - Brasília

The Brazilian Health Ministry today (May 20) included chloroquine and its derivative hydroxychloroquine in the treatment protocol for patients with mild symptoms of COVID-19. According to the ministry, it will be up to the doctor to decide to prescribe the drug, and patients to agree to sign a document stating they have been informed and agree with the terms.

The government cautions that, even though these are medications used in a number of protocols, with in vitro activity demonstrated against the new coronavirus, there are still no results from clinical trials proving the benefit in the treatment against COVID-19.

Nonetheless, in bringing the guidelines on the use of the drugs up to date, the Health Ministry considered the existence of a number of studies and the wide experience stemming from the use of chloroquine and hydroxychloroquine in the treatment of other infectious and chronic diseases in Brazilian public hospitals. The drug is originally recommended in the treatment of illnesses like malaria, lupus, and arthritis.
Click link above for full article.
Click to expand...
The guidelines cited many documents, including some completed and ongoing studies, about the drugs. Recent studies in France and China have found that hydroxychloroquine was associated with significantly shorten time of recovery and hospitalization and decreased of mortality rate.
 
Sandokan said:
The guidelines cited many documents, including some completed and ongoing studies, about the drugs. Recent studies in France and China have found that hydroxychloroquine was associated with significantly shorten time of recovery and hospitalization and decreased of mortality rate.
Click to expand...

An interesting test of medical advice is to ask the recommending doctor if they would give that advice to a member of their own family and then watch to see how much they squirm when they say "Yes.".

Have you ever wondered why so many ophthalmologists who recommend "corrective surgery" wear glasses?
 
Jack Hays said:




Hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19: a multinational registry ...

The Lancet·1 day ago









What a big Covid-19 study on malaria drugs tells us — and what it doesn't

Stat·1 day ago





No evidence of benefit for chloroquine and hydroxychloroquine in COVID-19 patients, study finds

ScienceDaily·1 day ago
Click to expand...


What about Ivermectin?


"Ivermectin was recently shown to inhibit the replication of SARS-CoV-2 in vitro at very high doses, but this effect has not yet been studied in vivo. The new study will investigate this question in a randomised trial. Twenty-four patients with mild disease and no risk factors will be given a single oral dose of ivermectin or placebo less than 48 hours after the onset of symptoms.

These newly diagnosed patients will not require hospitalisation, so follow-up will be carried out in their homes during their period of self-isolation. "We will give patients a single dose when they come to the clinic for a diagnostic test," explained Chaccour. "This will be followed by a month-long period of home-based follow-up, during which we will take five nasal swabs and monitor their symptoms. This will allow us to see whether ivermectin helps to clear the infection more quickly." The SARS-CoV 2 Ivermectin Navarra ISGlobal Trial (SAINT) is being funded by Clínica Universidad de Navarra and ISGlobal."



https://medicalxpress.com/news/2020-05-efficacy-ivermectin-covid-.html



//
 
Well, someone has to do something because the numbers just keep on getting worse.
 

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Trump is sending 2 million Hydroxychloroquin tablets to Brazil.....what does he have against Brazilians?
 
Gladiator said:
What about Ivermectin?


"Ivermectin was recently shown to inhibit the replication of SARS-CoV-2 in vitro at very high doses, but this effect has not yet been studied in vivo. The new study will investigate this question in a randomised trial. Twenty-four patients with mild disease and no risk factors will be given a single oral dose of ivermectin or placebo less than 48 hours after the onset of symptoms.

These newly diagnosed patients will not require hospitalisation, so follow-up will be carried out in their homes during their period of self-isolation. "We will give patients a single dose when they come to the clinic for a diagnostic test," explained Chaccour. "This will be followed by a month-long period of home-based follow-up, during which we will take five nasal swabs and monitor their symptoms. This will allow us to see whether ivermectin helps to clear the infection more quickly." The SARS-CoV 2 Ivermectin Navarra ISGlobal Trial (SAINT) is being funded by Clínica Universidad de Navarra and ISGlobal."



New study to assess the efficacy of ivermectin against COVID-19



//
Click to expand...

Ivermectin cannot be dosed you the levels required to inhibit the virus.

Lots of stuff can inhibit in test tubes.

It’s worth a flyer, I suppose, but it’s very unlikely to do anything.
 
Ethel2 said:
Trump is sending 2 million Hydroxychloroquin tablets to Brazil.....what does he have against Brazilians?
Click to expand...

<SARC>I guess that "Trump Pharmaceuticals" (a wholly owned subsidiary of "Trump International") couldn't get the US government to buy then at the expected 1,000% markup</SARC>.
 
Threegoofs said:
Ivermectin cannot be dosed you the levels required to inhibit the virus.

Lots of stuff can inhibit in test tubes.

It’s worth a flyer, I suppose, but it’s very unlikely to do anything.
Click to expand...

Do you ever get the impression that this thread has degenerated into arguments about HOW HARD it was appropriate to flog a dead horse?
 




Questions raised over hydroxychloroquine study which caused WHO to halt trials for Covid-19

The Guardian·23 hours ago









WHO Halts Clinical Trials of Hydroxychloroquine for COVID-19 as Study Highlights Higher Death Risks

The Weather Channel·1 day ago





images




UK experts welcome WHO's decision to pause Covid-19 trials of hydroxychloroquine drug advocated by Donald Trump

ITV News·2 days ago










 
Jack Hays said:
Read first, then post.
Click to expand...
I've read enough to know that an anti-parasitic has no beneficial qualities as a anti-viral, and as shown, it has lots of negatives. Beyond the probable need by you to boost the stock, it just so weird to see you digging for scraps from climate denier sources.....no check that....it isn't weird. It's par for the course.

PS...hows the Swedish method working out?
 
Gimmesometruth said:
I've read enough to know that a anti-parasitic has no beneficial qualities as a anti-viral, and as shown, it has lots of negatives. Beyond the probable need by you to boost the stock, it just so weird to see you digging for scraps from climate denier sources.....no check that....it isn't weird. It's par for the course.

PS...hows the Swedish method working out?
Click to expand...

But why are the deniers shilling for a drug?

So weird.
 
Gimmesometruth said:
I've read enough to know that a anti-parasitic has no beneficial qualities as a anti-viral, and as shown, it has lots of negatives. Beyond the probable need by you to boost the stock, it just so weird to see you digging for scraps from climate denier sources.....no check that....it isn't weird. It's par for the course.

PS...hows the Swedish method working out?
Click to expand...

Curry has sponsored a series of COVID-19 discussion threads. You might learn something.
We are months away from knowing how anyone's method has worked out.
Goodbye.
 
Threegoofs said:
But why are the deniers shilling for a drug?

So weird.
Click to expand...
Could be being invested in the stock(s)......but for Jack, it is all about being consistently on the wrong side....of everything. It takes a special talent to do that.
 
Jack Hays said:
Curry has sponsored a series of COVID-19 discussion threads. You might learn something.
Click to expand...
I learned a long time ago to laugh at climatologists leading any discussion on epidemiology.
We are months away from knowing how anyone's method has worked out.
Goodbye.
Click to expand...
No Jack, not when it comes to the Swedish method. That plan is in place in GOP states as we speak. Enjoying the carnage? Must be tough to see it from so high up.
 
Jack Hays said:
Read first, then post.
Click to expand...
Judith A. Curry was chair of the School of Earth and Atmospheric Sciences at the Georgia Institute of Technology unti she retired in 2017. She runs a climate blog and has been invited by Republicans on several occasions to testify at climate hearings about uncertainties in climate understanding and predictions. Climate scientists criticize her uncertainty-focused spiel for containing elementary mistakes and inflammatory assertions unsupported by evidence. Curry is a regular at Anthony Watts' denier blog, as well as Steve McIntyre's Climate Audit, another denier site. She has further embarrassed herself (and her university) by using refuted denier talking points and defending the Wegman Report, eventually admitting she hadn't even read it in the first place.[1] Curry has agreed with Trump's description of climate change as a "hoax", writing in 2016 that the UN's definition of manmade climate change "qualifies as a hoax".[2]

Judith Curry - SourceWatch
 
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