My personal experience from having known and worked with formerly home-schooled people is that they are, to a person, uniquely unsuited for real life.
They tend to be nervous, break down easily under stress.
They tend to get sick constantly.
I don't know if this is a result of never having been exposed to most of the contagions that others of us encounter at school as children, or what.
They tend to lack social skills and have no ability to resolve conflicts with peers and superiors.
However, this is only my personal experience, based on a small random sampling of formerly home-schooled people I've encountered over the years.
It's meaningless, even as anecdotal evidence, because for all I know every one of them might have also been abused, or had a chemical imbalance, or had some other weird factor in their lives which contributed to their growing up to be dysfunctional adults.
The empirical and statistical data I've seen seems to suggest that home-schooled kids turn out as well as or better than public school-educated kids, more or less on par with children who attend good private schools.