I think we should remain in most all of the organizations we now belong. NATO and the UN are a bit useless, but we suffer no consequence by staying. We have the largest veto power and as in Iraq, we act with or without consent.
Perhaps the most important, in my opinion at this point, is the Middle East Free Trade Initiative. I am an IR person and I think the key to solving the terrorist problem is by aiding in the establishment of a viable economy for the people of the ME. This will give the poor people of these countries an alternative to joining terror groups in order to support their families.