First of all, I find it difficult to cast a vote because I am not leaning. But to your questions,
I like to think that jobs and the economy are the most important issues. People with well paying jobs have a better perspective on things. When people are struggling to make ends meet and are afraid to lose their jobs, they tend to be less cooperative to lend a helping hand to others, fund ventures that they know little about or disagree with (green energy i.e.).
What's more, a sound economy and low unemployment assures revenue for most other necessities, like health care subsidies, entitlement programs, military, schools and so much more. But most importantly, it is our independence that is on the line. We need our jobs here, we have to stop borrowing money and becoming more dependent on countries that aren't very friendly.
The second most important issue is getting rid of the self serving and power hungry politicians who only have their own interests at heart. Most of them give good lip service, but lets face it, they seem to be very pleased with themselves while our country is going to hell. Party, candidate, it matters not. I can count on one hand the politicians is trust just a bit.