Close to "all of the above" . IMO, if a man has a good set up and is KNOWN to be proficient with the weapon, then more safe.. But, a "good set up " involves have the gun ready to fire within a second's notice.. which can backfire.
I feel that there are better systems of self defense, involving NO guns .
One :: true, complete and absolute gun control
Two :: police sworn to benefit the public
Three :: a government system that actually cares for all the people
Maybe by the year 2050 , not today , not even close