Without the license to operate as a business, commerce is limited or not allowed.
We as a people have determined that it is in the best interest of our society to restrict business/commerce to those that agree to follow certain rules. Among those rules are tax laws, anti-discrimination laws in hiring, paying and promotion of employees as offering of services or products for sale and many, many others.
If a person doesn't want to follow the laws of our society, then they can attempt to change the laws by legal means, or by electing like minded people to government to change the law through legislation.
There are a number of examples of the legal means in recent SCOTUS rulings, either affirming or changing these laws.