I would say yes with the caveat that a lot depends on what major events occur between now and 2016. I will say this, electoral politics/map plays right into the Democratic hands. Take the Six most populace states of CA, TX, FL, NY, IL, PA, the democrats own 4 of them with 124 electoral votes, the republicans, only TX 38 and Florida is a toss up that leans Democratic. But we won't count FL yet. Then the Democrats own the Northeast with the possible exception of NH, which is a toss up. So in those states I mentioned to include all the northeast the Dems are starting out with a 183-38 advantage with Florida and NH being toss ups.
Okay, the south is republican, but you can't add VA or NC, VA went to Obama the last years and NC was won by romney by a thin 100,000 votes or so, Let's leave those two states as toss ups and only count the south. The EV is now 183 to 118. Minnesota, Wisconsin and Michigan will go Dem, Indiana probably Republican and we can leave Ohio as a toss up. Total now is 219 to 129. 270 is needed to win.
Out west along with CA, OR, WA and Hawaii are strongly Democratic, make that total 242-129. The plain and rocky mountain states, Iowa is goes Democratic most of the time, Colorado and NM also, I would say in 2016 they will follow that trend, what about NV, lets leave NV as a toss up and then put the rest of the plains and mountain states in the GOP column. You now have 262 D 191 R with 270 to win. Now remember the toss up states, NH, VA, NC, OH, FL, NV. Whomever the GOP nominee is would have to win all of them with the exception of NH. I would say that it is high odds against it.
But the above scenero is generic Republican vs. generic Democrat. A charismatic candidate, a candidate that is as atractive to Indies as republicans could change the above and limit what is now a Democratic Electoral advantage. Once names are added, generic goes out the window or it doesn't depending on the name.