This is a ridiculous question because the rational answer must always
be yes, secession could possibly be appropriate, considering such extreme
hypothetical cases as if a national government were to attempt to single
out the population of a geographic area for enslavement (real slavery, as
in human beings reduced to property liable to be sold and bought, and
subject to unrestrained abuse by owners).
However, I decided to treat the question as if it considered only conditions
extending from what now actually exist to what might be remotely likely in
the foreseeable future.
In that light my answer was NO, secession is never acceptable.
I do not own a gun, and have lived a personal life of complete non-violence:
I have never harmed a hair on anyone’s head.
That will change if a true secession movement gets under way. I will buy a gun,
I will learn how to use it, and I will kill for the Union, for the unity of this, my beloved country,
the greatest place there is or has ever been. I cannot think of anyone who could
more deserve to die than any motherf u c k e r who tries to break it up.