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Nah, you'd pass out first.
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Is Chumlee dead???
- Thread starter MaggieD
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Nah, you'd pass out first.
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Just for giggles lets run some numbers related to THC ld50's.
I googled up this link, and no I am not going to pay for the paper to see what the inhalation results were, but since this is just a casual tossing around of numbers for giggles lets run with the info in the abstract.
ScienceDirect.com - Toxicology and Applied Pharmacology - Inhalation, parenteral and oral LD50 values of ?9-tetrahydrocannabinol in Fischer rats
I figure our best estimate here is to use the sesame oil number (abstract kind of explains more), 1270 mg/kg for the ld50. Lets just run with that. I figure inhalation is a less precise delivery method and there will be a lot that is not actually absorbed into the bloodstream, plus a vaporizer would not vaporize 100% of the THC but whatever.
Chumlee is not a small guy by any means, I figure 150 kg is a good estimate (330 lbs), but I will go with 100 kgs just for easier math. So using these figures, ld50 of 1270 mg/kg with a 100 kg guy we have 127 grams of THC to hit this ld50. This is grams of THC, not grams of marijuana mind you, so lets say it is the stickiest and ickiest bud available at ~25% THC. This means it would take 508 grams of marijuana to reach this ld50 (and remember this is based on a very loose assumption that 100% of the THC in the marijuana is actually absorbed into the blood).
But wait.. I dug up more stuff to play with!: Evaluation of a vaporizing device (Volcano®) for the pulmonary administration of tetrahydrocannabinol - Hazekamp - 2006 - Journal of Pharmaceutical Sciences - Wiley Online Library
So lets add in these numbers.. lets round off instead of 54% we use 50% of the THC in the marijuana made it into the balloon of the vaporizers, and 35% of that got exhaled (and if he was seriously power smoking the amount necessary I am sure there would be far far more exhaled than that). Plugging in these numbers we are now up to over 1500 grams of the super sticky bud needed to get to that ld50.
Crunching these numbers we get 3.5 pounds of marijuana needed to hit the ld50 for a 100kg's. Chumlee is more like 150 kgs, so that pushes it over the 5 pounds of the absolute best weed around needed to kill him - and I do not care how quickly he smoked, there is no way he would be able to inhale 5 pounds of pot fast enough for all the THC to still be active in his bloodstream.
The verdict here? MYTH BUSTED :2razz::mrgreen:
I googled up this link, and no I am not going to pay for the paper to see what the inhalation results were, but since this is just a casual tossing around of numbers for giggles lets run with the info in the abstract.
ScienceDirect.com - Toxicology and Applied Pharmacology - Inhalation, parenteral and oral LD50 values of ?9-tetrahydrocannabinol in Fischer rats
I figure our best estimate here is to use the sesame oil number (abstract kind of explains more), 1270 mg/kg for the ld50. Lets just run with that. I figure inhalation is a less precise delivery method and there will be a lot that is not actually absorbed into the bloodstream, plus a vaporizer would not vaporize 100% of the THC but whatever.
Chumlee is not a small guy by any means, I figure 150 kg is a good estimate (330 lbs), but I will go with 100 kgs just for easier math. So using these figures, ld50 of 1270 mg/kg with a 100 kg guy we have 127 grams of THC to hit this ld50. This is grams of THC, not grams of marijuana mind you, so lets say it is the stickiest and ickiest bud available at ~25% THC. This means it would take 508 grams of marijuana to reach this ld50 (and remember this is based on a very loose assumption that 100% of the THC in the marijuana is actually absorbed into the blood).
But wait.. I dug up more stuff to play with!: Evaluation of a vaporizing device (Volcano®) for the pulmonary administration of tetrahydrocannabinol - Hazekamp - 2006 - Journal of Pharmaceutical Sciences - Wiley Online Library
So lets add in these numbers.. lets round off instead of 54% we use 50% of the THC in the marijuana made it into the balloon of the vaporizers, and 35% of that got exhaled (and if he was seriously power smoking the amount necessary I am sure there would be far far more exhaled than that). Plugging in these numbers we are now up to over 1500 grams of the super sticky bud needed to get to that ld50.
Crunching these numbers we get 3.5 pounds of marijuana needed to hit the ld50 for a 100kg's. Chumlee is more like 150 kgs, so that pushes it over the 5 pounds of the absolute best weed around needed to kill him - and I do not care how quickly he smoked, there is no way he would be able to inhale 5 pounds of pot fast enough for all the THC to still be active in his bloodstream.
The verdict here? MYTH BUSTED :2razz::mrgreen: