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A recent study, looking at the recent rise in the death rate for white Americans between the ages of 30 and 64, notes that all other high income nations continue to show decreases in death rates.
and a possible explanation
. . . all 5-y age groups between 30–34 and 60–64 have witnessed marked and similar increases in mortality from the sum of drug and alcohol poisoning, suicide, and chronic liver disease and cirrhosis over the period 1999–2013
and a possible explanation
Although the epidemic of pain, suicide, and drug overdoses
preceded the financial crisis, ties to economic insecurity are possible.
After the productivity slowdown in the early 1970s, and with
widening income inequality, many of the baby-boom generation are
the first to find, in midlife, that they will not be better off than were
their parents. Growth in real median earnings has been slow for this
group, especially those with only a high school education. However,
the productivity slowdown is common to many rich countries, some
of which have seen even slower growth in median earnings than the
United States, yet none have had the same mortality experience
(lanekenworthy.net/shared-prosperity and ref. 30). The United States
has moved primarily to defined-contribution pension plans with
associated stock market risk, whereas, in Europe, defined-benefit
pensions are still the norm. Future financial insecurity may weigh
more heavily on US workers