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Thread: Scientists cure cancer, but no one takes notice

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    Scientists cure cancer, but no one takes notice

    Scientists cure cancer, but no one takes notice

    Canadian researchers find a simple cure for cancer, but major pharmaceutical companies are not interested.

    Researchers at the University of Alberta, in Edmonton, Canada have cured cancer last week, yet there is a little ripple in the news or in TV. It is a simple technique using a very basic drug. The method employs dichloroacetate, which is currently used to treat metabolic disorders. So, there is no concern of side effects or about their long term effects.

    This drug doesn’t require a patent, so anyone can employ it widely and cheaply compared to the costly cancer drugs produced by major pharmaceutical companies.

    Canadian scientists tested this dichloroacetate (DCA) on human’s cells; it killed lung, breast and brain cancer cells and left the healthy cells alone. It was tested on Rats inflicted with severe tumors; their cells shrank when they were fed with water supplemented with DCA. The drug is widely available and the technique is easy to use, why the major drug companies are not involved? Or the Media interested in this find?

    ...

    Pharmaceutical companies are not investing in this research because DCA method cannot be patented, without a patent they can’t make money, like they are doing now with their AIDS Patent. Since the pharmaceutical companies won’t develop this, the article says other independent laboratories should start producing this drug and do more research to confirm all the above findings and produce drugs. All the groundwork can be done in collaboration with the Universities, who will be glad to assist in such research and can develop an effective drug for curing cancer.
    What a very astonishing find! I wish the universities well in their ongoing drug development.

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    Re: Scientists cure cancer, but no one takes notice

    Interesting, though I'll point out it's from 2007, but here's the original study, so if anyone with a brain can tell us what it means. *cough*Digsbe*cough*

    SUMMARY
    The unique metabolic profile of cancer (aerobic glycolysis) might confer apoptosis resistance and be
    therapeutically targeted. Compared to normal cells, several human cancers have high mitochondrial
    membrane potential (DJm) and low expression of the K+ channel Kv1.5, both contributing to apoptosis
    resistance. Dichloroacetate (DCA) inhibits mitochondrial pyruvate dehydrogenase kinase (PDK),
    shifts metabolism from glycolysis to glucose oxidation, decreases DJm, increases mitochondrial
    H2O2, and activates Kv channels in all cancer, but not normal, cells; DCA upregulates Kv1.5 by an
    NFAT1-dependent mechanism. DCA induces apoptosis, decreases proliferation, and inhibits tumor
    growth, without apparent toxicity.Molecular inhibition of PDK2 by siRNA mimics DCA. The mitochondria-
    NFAT-Kv axis and PDK are important therapeutic targets in cancer; the orally available DCA is
    a promising selective anticancer agent.
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    Re: Scientists cure cancer, but no one takes notice

    Quote Originally Posted by spud_meister View Post
    Interesting, though I'll point out it's from 2007, but here's the original study, so if anyone with a brain can tell us what it means. *cough*Digsbe*cough*
    I'm no Biologist but as I understand it, cancer cells use sugars to fuel themselves and in the process create a barrier around their cell walls which makes them immune to our normal body defences. It appears that DCA strangles this mechanism meaning that cancer cells are open to attack from the bodies normal immune defences.

    It sounds like what we need is a country with a major national health service that is interested in developing and testing an un-patentable drug.
    Last edited by William Rea; 05-14-11 at 03:49 AM.

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    Re: Scientists cure cancer, but no one takes notice

    Quote Originally Posted by Temporal View Post
    Scientists cure cancer, but no one takes notice



    What a very astonishing find! I wish the universities well in their ongoing drug development.
    Pharmaceutical companies just like any other company exist to make profits. A cancer cure would put a huge dent in their profits.
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    Re: Scientists cure cancer, but no one takes notice

    Quote Originally Posted by jamesrage View Post
    Pharmaceutical companies just like any other company exist to make profits. A cancer cure would put a huge dent in their profits.
    And if this is true(which I doubt because it is 4 years old, and something like this would have caused a stir) they should all be tried for all the deaths, and money lost by people affected with cancer.
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    Re: Scientists cure cancer, but no one takes notice

    Quote Originally Posted by Your Star View Post
    And if this is true(which I doubt because it is 4 years old, and something like this would have caused a stir) they should all be tried for all the deaths, and money lost by people affected with cancer.
    The problem appears to be that no one has run with it and really checked out the claims in humans. DCA is an approved drug already so a trial shouldn't be too difficult to set up as long as the patients are prepared to be in the trial.

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    Re: Scientists cure cancer, but no one takes notice

    Quote Originally Posted by jamesrage View Post
    Pharmaceutical companies just like any other company exist to make profits. A cancer cure would put a huge dent in their profits.
    This is why government funding is so very important in the medical field.

    Should companies bury cures to maintain profit on purpose, the CEO's of those companies should be arrested and executed in my opinion.

    A little too regressive for some people?

    I could live with it.

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    Re: Scientists cure cancer, but no one takes notice

    Quote Originally Posted by Jetboogieman View Post
    This is why government funding is so very important in the medical field.

    Should companies bury cures to maintain profit on purpose, the CEO's of those companies should be arrested and executed in my opinion.

    A little too regressive for some people?

    I could live with it.
    I wouldn't go that far. You can't blame private pharmaceutical corporations for doing what they are created to do. They are not in business to find cures for cancer, but to make profits for their investors (obviously a much more important goal) and I'm not even being ironic.

    This is why free-market capitalism is incapable of providing everything that society requires.
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    Re: Scientists cure cancer, but no one takes notice

    Quote Originally Posted by Andalublue View Post
    I wouldn't go that far. You can't blame private pharmaceutical corporations for doing what they are created to do. They are not in business to find cures for cancer, but to make profits for their investors (obviously a much more important goal) and I'm not even being ironic.

    This is why free-market capitalism is incapable of providing everything that society requires.
    We'll have to agree to disagree on this one.

    In my opinion if the drug companies of this world United, pulled their recources together and did all they could, we could cure every single ailment known to mankind in the next 20 years.

    Probably.

    But we choose not to, to make a quick buck here and there.

    It is a travesty to mankind that anything to do with the health of the human being is a money making scheme.

    Its idealistic thinking I know, but I stand behind it, as is my belief in the way the world SHOULD be.

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    Re: Scientists cure cancer, but no one takes notice

    Quote Originally Posted by Jetboogieman View Post
    We'll have to agree to disagree on this one.

    In my opinion if the drug companies of this world United, pulled their recources together and did all they could, we could cure every single ailment known to mankind in the next 20 years.
    They could, but why would they? What would be the benefit in profit terms were this to happen? I think it would have a negative effect on profits, don't you?
    But we choose not to, to make a quick buck here and there.
    The bucks they make are not quick, they take many years and much research to achieve, and they are not doing this for the benefit of society at large, but to make a profit. Any benefit they provide to the wider society is a serendipitous by-product of making money. That's why it's called capitalism, because it's driven by the concerns of capital i.e. investment money.
    It is a travesty to mankind that anything to do with the health of the human being is a money making scheme.
    Of course it is, but that it the system that most people here seem to believe is indispensible to the well-being of human society. Go figure.

    Its idealistic thinking I know, but I stand behind it, as is my belief in the way the world SHOULD be.
    To me, you appear to be getting frustrated at the natural operation of the current system. I think your ire would best be directed at the fundaments of the system, not its consequences.
    "The crisis will end when fear changes sides" - Pablo Iglesias Turrión

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