Douglas Holtz-Eakin in addition to being director of the CBO from 2003-2005, was also the chief economic policy adviser to U.S. Senator John McCain‘s 2008 presidential campaign. He's the president of the American Action Forum, a self-admitted center-right policy institute that includes members such as Norm Coleman, Jeb Bush and Tom Ridge.
Here are a couple of rebuttals/explanations relative to Holtz-Eakin's Op-Ed.
Center on Budget and Policy Priorites
Health Reform Will Reduce the Deficit — Center on Budget and Policy Priorities
and the CBO themselves
Director's Blog Blog Archive Uncertainty in Estimates for Health Care Legislation