To some conservatives, the Perez confirmation is already emerging as the most galling consequence of the filibuster deal, even though many Republicans said he would have gotten the 60 votes to break a filibuster regardless.
Conservative Republicans in the House have spent months accusing Mr. Perez of being overly partisan, antireligious, and litigious to a fault. The House Oversight and Government Reform Committee had outstanding subpoenas issued against Mr. Perez, demanding records on a deal he struck with the city of St. Paul to drop a lawsuit involving public housing conditions in what some Republicans called a quid pro quo.
Republicans involved in that investigation say they have been left high and dry.
“We lost, he won,” said Representative Jim Jordan, Republican of Ohio and a senior member of the committee.
Senator Mike Lee, Republican of Utah, echoed the concerns of many Republicans who have accused Mr. Perez of selecting cases based on political motivation and, in some instances, racial bias.
“Simply put, there’s no shortage of reasons why Mr. Perez should not be confirmed,” he said on the Senate floor.
Mr. Obama hailed the confirmation of Mr. Perez and others “who have waited far too long for the yes-or-no votes they deserve.”
“Tom has lived the American dream himself, and has dedicated his career to keeping it within reach for hard-working families across the country. At the Department of Labor, Tom will help us continue to grow our economy, help businesses create jobs, make sure workers have the skills those jobs require, and ensure safe workplaces and economic opportunity for all,” the president said.