Special Precautions & Warnings:
Pregnancy and breast-feeding: Intravaginal progesterone gel is LIKELY SAFE when used as part of infertility treatment. But don’t use progesterone otherwise. It’s also best not to use progesterone if you are breast-feeding. Not enough is known about how it might affect a nursing infant.
Arterial disease: Don’t use progesterone if you have arterial disease.
Breast cancer: Avoid use unless you are directed to do so by your healthcare provider.
Depression: Get your healthcare provider’s advice first before using progesterone if you have major depression now or a history of major depression.
Liver disease: Progesterone might make liver disease worse. Don’t use it.
Vaginal bleeding: If you have undiagnosed vaginal bleeding, don’t use progesterone.